Polyuria
The production and excretion of an abnormally large volume of urine.
💬 In Plain English
Polyuria means producing an unusually large volume of urine. It is different from pollakiuria (straining to produce tiny frequent drops during a bladder infection). In polyuria, the kidneys cannot hold onto water, so the pet produces massive, pale, watery puddles or large, heavy clumps in the litter box. House-trained dogs may suddenly have large accidents indoors overnight or wake owners repeatedly to go outside.
🔬 Clinical & Technical Depth
For Vets & TechniciansFormal Clinical Definition
Urine output exceeding normal physiologic thresholds (>50 mL/kg/day in canines and felines), distinct from pollakiuria (increased frequency of small-volume micturition) or urinary incontinence (involuntary leakage).
Why Veterinarians Use It
Veterinarians assess polyuria through urine specific gravity (USG) on a refractometer to determine if urine is inappropriately dilute (hyposthenuric or isosthenuric).
Clinical Context Encountered
Frequently reported alongside polydipsia (as "PU/PD") during investigations into endocrine, renal, or hepatic disease.
Clinical Reference Guide (Clinical Symptom)
- •If a previously polyuric animal suddenly stops producing urine entirely (anuria), this is a critical emergency requiring immediate veterinary attention.
❓ Questions to Ask Your Veterinarian
Take these actionable questions with you to your next clinic visit or appointment:
- 1Is my pet producing large volumes of dilute urine (polyuria) or straining to produce frequent tiny amounts (pollakiuria)?
- 2What was the exact Urine Specific Gravity (USG) number on the urinalysis?
- 3Is there glucose or protein spilling into the urine?
- 4Should a first-morning urine sample be collected for testing?
Academic & Clinical References
- Polyuria and Polydipsia in AnimalsOrganization: Merck Veterinary Manual • Accessed: 2026-01-10https://www.merckvetmanual.com/urinary-system/noninfectious-diseases-of-the-urinary-system-in-small-animals/polyuria-and-polydipsia-in-animals